CHEMBL6058122


SMILES O=C(O)c1ccc(CCc2cccc3c2N(Cc2cccc(F)c2)CC3)cc1
InChIKey IAWBENGNIVXQLE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 7.42 8.06 8.7 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 6.05 7.29 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 7.46 7.46 7.46 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 6.91 7.53 8.14 ChEMBL