CHEMBL6051481


SMILES O=c1c(P(=O)(O)O)nc2ccccc2n1[C@H]1C[C@H]2CC[C@@H](C1)N2C12CC3CC(CC1C3)C2
InChIKey XAHBWTCSLWOLOX-NUILKOFCSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 455.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 4.7 4.7 4.7 ChEMBL
κ OPRK Human Opioid A pKi 5.4 5.4 5.4 ChEMBL
μ OPRM Human Opioid A pKi 6.18 6.18 6.18 ChEMBL
NOP OPRX Human Opioid A pKi 7.23 7.23 7.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pEC50 4.7 4.7 4.7 ChEMBL
NOP OPRX Human Opioid A pEC50 6.71 6.71 6.71 ChEMBL