CHEMBL6048201


SMILES CN(C)[C@]1(c2ccccc2)CC[C@]2(CC1)CN(CC(C)(C)C#N)C(=O)N2CC1(F)CC1
InChIKey DZLAOMAFKCXUPK-PLQXJYEYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 426.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 6.15 6.46 7.08 ChEMBL
μ OPRM Human Opioid A pKi 5.53 5.53 5.53 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database