CHEMBL6045878


SMILES Cc1ncc2c(n1)CCN(CCN1CCC(c3noc4ccccc34)CC1)C2=O
InChIKey IERLWRGUKNBJKE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.2 8.22 8.27 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.0 8.17 8.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.04 6.27 6.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database