CHEMBL6045107


SMILES CC(Oc1ccc(Br)cc1OC1CNC1)c1cccc(Cl)c1
InChIKey LXUUWPTWSIBEAC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 381.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.16 7.16 7.16 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database