CHEMBL6034636


SMILES Cc1ccc(C(=O)N[C@H]2CC[C@H](CCN3CCN(c4nsc5ccccc45)CC3)CC2)[nH]1
InChIKey CVDQBFXJSLNCIC-MXVIHJGJSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 451.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.75 8.75 8.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.89 8.89 8.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.59 8.59 8.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database