CHEMBL6195809


SMILES CC1C[C@@H]2C[C@H](C1)C[C@H](N1[C@@H]3CCC[C@H]1C[C@@H](n1c(=O)c(P(=O)(O)OCOC(=O)c4ccccc4)nc4ccccc41)C3)C2
InChIKey DGUBECAMYJKRNF-SWEUAHBUSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 619.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 5.28 5.28 5.28 ChEMBL
κ OPRK Human Opioid A pKi 7.42 7.42 7.42 ChEMBL
μ OPRM Human Opioid A pKi 6.4 6.4 6.4 ChEMBL
NOP OPRX Human Opioid A pKi 7.91 7.91 7.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 4.7 4.7 4.7 ChEMBL
μ OPRM Human Opioid A pEC50 4.7 4.7 4.7 ChEMBL
NOP OPRX Human Opioid A pEC50 7.86 7.86 7.86 ChEMBL