CHEMBL6195808


SMILES C[C@@H]1C[C@@H]2C[C@H](C1)C[C@H](N1[C@@H]3CCC[C@H]1C[C@@H](n1c(=O)c(CCP(=O)(O)O)nc4ccccc41)C3)C2
InChIKey PSYXPVKXUPRUNH-PHWOVJDESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 513.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.47 8.47 8.47 ChEMBL
δ OPRD Human Opioid A pKi 5.23 5.23 5.23 ChEMBL
κ OPRK Human Opioid A pKi 7.11 7.11 7.11 ChEMBL
μ OPRM Human Opioid A pKi 6.89 6.89 6.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 8.4 8.4 8.4 ChEMBL
κ OPRK Human Opioid A pEC50 4.7 4.7 4.7 ChEMBL
μ OPRM Human Opioid A pEC50 4.7 4.7 4.7 ChEMBL