CHEMBL6195807


SMILES C[C@@H]1C[C@@H]2C[C@H](C1)C[C@H](N1[C@@H]3CCC[C@H]1C[C@@H](n1c(=O)c(/C=C/P(=O)(O)O)nc4ccccc41)C3)C2
InChIKey GWUUNKXMMADFKY-XBIYMARFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 511.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.26 8.26 8.26 ChEMBL
κ OPRK Human Opioid A pKi 6.39 6.39 6.39 ChEMBL
μ OPRM Human Opioid A pKi 6.3 6.3 6.3 ChEMBL
δ OPRD Human Opioid A pKi 5.25 5.25 5.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 8.05 8.05 8.05 ChEMBL
κ OPRK Human Opioid A pEC50 4.7 4.7 4.7 ChEMBL
μ OPRM Human Opioid A pEC50 4.7 4.7 4.7 ChEMBL