PHENYLPROPANOLAMINE


SMILES CC(N)C(O)c1ccccc1
InChIKey DLNKOYKMWOXYQA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 151.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Rat Adrenoceptors A pKi 6.58 6.58 6.58 ChEMBL
α1B ADA1B Golden hamster Adrenoceptors A pKi 5.02 5.02 5.02 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKi 5.07 5.07 5.07 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 5.01 5.01 5.01 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.56 6.56 6.56 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.29 8.29 8.29 Drug Central
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.29 8.29 8.29 Drug Central
α2A ADA2A Human Adrenoceptors A pKi 8.18 8.18 8.18 Drug Central
α2B ADA2B Human Adrenoceptors A pKi 8.19 8.19 8.19 Drug Central
α2C ADA2C Human Adrenoceptors A pKi 8.18 8.18 8.18 Drug Central
α1D ADA1D Rat Adrenoceptors A pKi 8.29 8.29 8.29 Drug Central
α1A ADA1A Rat Adrenoceptors A pKi 8.3 8.3 8.3 Drug Central
α2B ADA2B Rat Adrenoceptors A pKi 8.18 8.18 8.18 Drug Central
α1B ADA1B Golden hamster Adrenoceptors A pKi 8.3 8.3 8.3 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pEC50 4.12 4.12 4.12 ChEMBL