CHEMBL6010233


SMILES O=C(O)c1ccc(CCc2cccc3c2N(Cc2cccc(C(F)(F)F)c2)CC3)cc1
InChIKey JBRUGSGYLFSCNW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 8.15 8.15 8.15 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 5.93 6.15 6.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 7.82 7.82 7.82 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 6.73 6.73 6.73 ChEMBL