CHEMBL6004129


SMILES COc1ccccc1N1CCN(CCCCOc2ccc3c(c2)NC(=O)CO3)CC1
InChIKey ZQIBMJPPTOOPCH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.19 9.19 9.19 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.93 6.93 6.93 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.52 9.52 9.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 9.01 9.01 9.01 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.58 6.58 6.58 ChEMBL
D2 DRD2 Human Dopamine A pIC50 9.01 9.01 9.01 ChEMBL