CHEMBL6003924


SMILES CN(C)[C@]1(c2ccccc2)CC[C@]2(CC1)CN(c1cnc(-c3ccc(C#N)cc3)nc1)C(=O)N2
InChIKey KNYCKNQTWLYKLN-MKPDMIMOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 452.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.05 8.05 8.05 ChEMBL
μ OPRM Human Opioid A pKi 5.43 5.43 5.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database