CHEMBL5995915


SMILES CN(C)[C@]1(c2ccccc2)CC[C@]2(CC1)CN(c1cnc(-c3cccc4c3CC(=O)N4)nc1)C(=O)N2
InChIKey UGKWPQWTPPVLMQ-HNRBIFIRSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 482.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.41 8.05 8.7 ChEMBL
μ OPRM Human Opioid A pKi 5.48 5.65 5.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database