CHEMBL5995499


SMILES CN[C@]1(c2cccc(F)c2)CC[C@]2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CC1
InChIKey IZYPXPNEVSAQPS-ZRZAMGCNSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 477.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.05 8.05 8.05 ChEMBL
μ OPRM Human Opioid A pKi 5.84 5.84 5.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database