CHEMBL5988653


SMILES COc1cccc(OC(=O)N[C@H]2CC[C@H](CCN3CCN(c4nsc5ccccc45)CC3)CC2)c1
InChIKey PKQCPDFILCUSCX-MEMLXQNLSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 494.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.97 8.32 8.68 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.85 8.85 8.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.71 8.71 8.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database