CHEMBL5976918


SMILES O=C(Cc1coc2ccccc12)N[C@H]1CC[C@H](CCN2CCN(c3nsc4ccccc34)CC2)CC1
InChIKey YRFHSWLWNMFJNN-AFARHQOCSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 502.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.12 8.12 8.12 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.73 8.73 8.73 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.64 9.64 9.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database