CHEMBL5970135


SMILES Cc1ncc2c(=O)n(CCN3CCN(c4noc5ccccc45)CC3)ccc2n1
InChIKey PHAVNSHDZRSZRT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 390.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.41 6.96 8.07 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.91 7.31 8.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.8 5.8 5.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database