CHEMBL5966738


SMILES O=C(O)c1ccc(CCc2cccc3c2N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC3)cc1
InChIKey NXOQDGHYBZYSSC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 493.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 7.21 8.37 9.52 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 5.92 6.6 7.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 7.96 7.96 7.96 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 7.15 7.15 7.15 ChEMBL