CHEMBL5965882


SMILES O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(c3nsc4ccccc34)CC2)CC1)c1cc2cc(Cl)ccc2s1
InChIKey AXFCFTMMGTUXSG-XYWHTSSQSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 574.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.74 8.19 9.1 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.47 8.75 9.04 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.01 8.01 8.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database