CHEMBL5965086


SMILES O=C1c2ncccc2CCN1CCN1CCC(c2noc3cc(F)ccc23)CC1
InChIKey RNOHWLCDKWAPGB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 394.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.86 7.94 8.01 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.62 9.09 9.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.32 6.69 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database