CHEMBL5958700


SMILES Cn1cnc2ccc(OCCCCN3CCN(c4cccc(C(F)(F)F)c4)CC3)cc2c1=O
InChIKey IGGKHEHGJTUIOP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 460.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.13 8.13 8.13 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.91 7.91 7.91 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.61 7.61 7.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database