CHEMBL5956456


SMILES O=C(O)c1ccc(CCc2cccc3c2N(Cc2cc(F)cc(F)c2)CC3)cc1
InChIKey UULDEIOPVNSQAZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 393.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 6.94 7.43 7.92 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 6.38 6.71 7.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 6.89 7.4 7.92 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 6.69 7.03 7.37 ChEMBL