CHEMBL5951761


SMILES O=C(c1ccc(F)c(Cl)c1)N1CCC(F)(CNCCOc2cccc(N3CCCC3)n2)CC1
InChIKey AZJORHGFWCVUSE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 478.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 6.2 6.2 6.2 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.77 8.96 9.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 6.58 7.11 7.57 ChEMBL