CHEMBL5972737


SMILES COc1nc(C#N)ncc1N1C[C@]2(C[C@@](c3ccccc3)(N(C)C)C2)N(CC2CCC2)C1=O
InChIKey OMWVZAUUCVNDMM-SOAUALDESA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 446.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.0 7.0 7.0 ChEMBL
μ OPRM Human Opioid A pKi 8.52 8.52 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database