CHEMBL5937360


SMILES O=C1c2ncccc2CCN1CCN1CCN(c2noc3cc(F)ccc23)CC1
InChIKey HNFGNFPOEVJRAY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 395.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.79 7.05 7.58 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.82 8.51 8.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.77 5.98 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database