CHEMBL5918269


SMILES CN(C)[C@]1(c2ccccc2)CC[C@]2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CC1CCC1
InChIKey PGSBGXIRVLTDIA-WMPKNSHKSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 444.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.52 9.52 9.52 ChEMBL
μ OPRM Human Opioid A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database