CHEMBL5915272


SMILES O=c1c2cnc(C(F)(F)F)cc2ccn1CCN1CCN(c2nsc3ccccc23)CC1
InChIKey IQZBAUJGDCLIDU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 459.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.48 8.48 8.48 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.61 8.61 8.61 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.42 6.42 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database