CHEMBL5913353


SMILES O=C1c2cnc(C(F)(F)F)cc2CCN1CCN1CCN(c2nsc3ccccc23)CC1
InChIKey UWFAHEVNGNMETJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 461.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.79 8.79 8.79 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.59 8.59 8.59 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.99 5.99 5.99 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database