CHEMBL5907314


SMILES O=C(O)c1ccc(CCc2cccc3c2N(Cc2ccc(F)cc2)CC3)cc1
InChIKey JNZTWQMOLKUDBA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 7.02 7.43 7.85 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 6.21 6.79 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 7.54 7.54 7.55 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 6.35 7.25 8.15 ChEMBL