CHEMBL5878995


SMILES C[C@@H]1CN(c2nc(Cl)cc(C#N)n2)C[C@H](C)N1C(=O)NCCC1CCN(Cc2ccccc2)CC1
InChIKey LOXIAQJMZROLGY-BGYRXZFFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 495.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.26 7.26 7.26 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.26 6.26 6.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database