CHEMBL5869713


SMILES Cn1c(=O)c2cc(OCCCN3CCN(c4cccc5sccc45)CC3)ccc2n(C)c1=O
InChIKey WTTUGTZNJAQTRA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 464.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 6.81 6.81 6.81 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.59 7.59 7.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database