CHEMBL5869160


SMILES CCOP(=O)(OCC)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C23CC4CC(CC2C4)C3)c1=O
InChIKey CVBWYFBEARUZOC-LJCUTECVSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 511.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 4.7 4.7 4.7 ChEMBL
NOP OPRX Human Opioid A pKi 7.32 7.32 7.32 ChEMBL
κ OPRK Human Opioid A pKi 7.5 7.5 7.5 ChEMBL
μ OPRM Human Opioid A pKi 6.37 6.37 6.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 6.74 6.74 6.74 ChEMBL
κ OPRK Human Opioid A pEC50 4.7 4.7 4.7 ChEMBL
μ OPRM Human Opioid A pEC50 4.7 4.7 4.7 ChEMBL