CHEMBL5868777


SMILES O=C(c1ccc(F)c(Cl)c1)N1CCC(F)(CNCCOc2cc(F)ccn2)CC1
InChIKey VGNJZLFABGNCBA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 427.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 10.3 10.32 10.35 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.05 6.05 6.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.47 8.22 9.36 ChEMBL