CHEMBL5857085


SMILES O=c1c2cnc(C(F)(F)F)cc2ccn1CCN1CCN(c2noc3ccccc23)CC1
InChIKey SIFJISLSFCWHFO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 443.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.41 7.41 7.41 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database