CHEMBL5852486


SMILES Cn1nc2c(c1Br)C(=O)N(CCN1CCN(c3nsc4ccccc34)CC1)CC2
InChIKey LODDBBDHOKVEHS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 474.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.01 9.01 9.01 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.27 9.27 9.27 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.63 6.63 6.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database