CHEMBL5845312


SMILES COC(=O)N[C@H]1CC[C@@H](CCN2CCN(c3nsc4ccccc34)CC2)CC1
InChIKey GJKBMWIJPUSQGX-CALCHBBNSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 402.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.21 8.4 8.59 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.91 8.91 8.91 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.65 8.65 8.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database