CHEMBL5840631


SMILES COc1cc2c(cn1)C(=O)N(CCN1CCC(c3noc4ccccc34)CC1)CC2
InChIKey NPUHZBJVAWACGT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 406.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.11 9.58 9.82 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.62 8.73 8.78 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.72 6.49 6.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database