CHEMBL5840586


SMILES COc1ccc2oc(C(=O)N[C@H]3CC[C@H](CCN4CCN(c5nsc6ccccc56)CC4)CC3)cc2c1
InChIKey UEUHNMQUIFFWEA-AQYVVDRMSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 518.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.21 8.21 8.21 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.95 8.95 8.95 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.98 8.98 8.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database