CHEMBL5840380


SMILES Cc1nc2ccc(OCCCN3CCN(c4cccc(C(F)(F)F)c4)CC3)cc2c(=O)n1C
InChIKey ZHBTYBBXWTXWRS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 460.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.66 7.66 7.66 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.08 8.08 8.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database