CHEMBL5934096


SMILES COc1cc(C(F)(F)F)c(OC)cc1C1CCCNC1
InChIKey NZKYTYHIERLZBG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 289.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.12 6.12 6.12 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.63 5.63 5.63 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.21 6.21 6.21 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.07 7.07 7.07 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.38 7.38 7.38 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.78 7.78 7.78 ChEMBL
A2A AA2AR Human Adenosine A pKi 5.85 5.85 5.85 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.18 6.18 6.18 ChEMBL
A2B AA2BR Human Adenosine A pKi 6.09 6.09 6.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database