CHEMBL5882228


SMILES C[C@@H](Oc1ccc(Cl)cc1OC1CNC1)c1cccc(C(F)(F)F)c1
InChIKey AJVPXLKAJYXQNL-LLVKDONJSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 371.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.13 6.13 6.13 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.69 6.69 6.69 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.03 6.03 6.03 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database