CHEMBL5823313


SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(c3nsc4ccccc34)CC2)CC1)OCc1cccs1
InChIKey LWEJANPMNUMGMB-MXVIHJGJSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 484.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.32 8.54 8.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.6 8.6 8.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database