CHEMBL5815957


SMILES CN(C)[C@]1(c2cccc(F)c2)C[C@@]2(CN(c3ccc(OC(F)(F)F)cn3)C(=O)N2CC2(O)CCC2)C1
InChIKey JPLDSLFQFNCDAC-QUPDYRNUSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 508.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.92 7.92 7.92 ChEMBL
μ OPRM Human Opioid A pKi 6.47 6.47 6.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database