CHEMBL5805070


SMILES CN(C)[C@]1(c2ccccc2)CC[C@]2(CC1)CN(C1CCN(c3cncnc3)CC1)C(=O)N2CC1(O)CCC1
InChIKey IEWPWVIQANENFH-KRKINAOUSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 518.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.64 7.87 8.1 ChEMBL
μ OPRM Human Opioid A pKi 5.7 5.95 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database