CHEMBL5790341


SMILES O=C1CCc2cc(OCCCN3CCC(C4=NOC5C=C(F)C=CC45)CC3)ccc2N1
InChIKey OCNUPGFDBUFRFR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.45 7.45 7.45 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.25 8.25 8.25 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.63 7.63 7.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database