CHEMBL5782641


SMILES CN(C)[C@]1(c2ccccc2)CC[C@]2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CCC1
InChIKey ZRPCPFCBODJNBN-PLQXJYEYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 487.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.0 9.2 9.4 ChEMBL
μ OPRM Human Opioid A pKi 6.96 7.2 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database