CHEMBL5773534


SMILES COc1cnc([C@H](C)[C@H](C)S(=O)(=O)Nc2nnc(-c3ccn(C)n3)n2-c2c(OC)ncnc2OC)nc1
InChIKey VAELBRYCYADNPS-OLZOCXBDSA-N

Chemical properties

Hydrogen bond acceptors 14
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 530.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
apelin APJ Human Apelin A pEC50 8.57 9.21 9.85 ChEMBL