CHEMBL5750025


SMILES COc1c2c(nn1C)CCN(CCN1CCN(c3nsc4ccccc34)CC1)C2=O
InChIKey SJAVWFDEBXEFCQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.79 8.79 8.79 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.34 9.34 9.34 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.09 6.09 6.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database