CHEMBL5746640


SMILES CN(C)[C@]1(c2ccccc2)CC[C@]2(CC1)CN(CC(=O)Nc1cnc(C#N)nc1)C(=O)N2CC1CCC1
InChIKey AWYQASHEYOOKME-HNRBIFIRSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 501.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 7.71 7.71 7.71 ChEMBL
NOP OPRX Human Opioid A pKi 8.82 8.82 8.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database